A number of antibiotic resistance initiatives focusing on raising awareness have been taken across the globe, but an initiative that focuses on accelerated antibiotic and diagnostic development has not been created. The challenge of dealing with an evolving pathogen is unique, often one that cannot be solved using conventional approaches. Academia offers creative ideas to address antimicrobial resistance, but often lacks focus and resources to convert ideas into products that will reach patients. On the other hand, industry has the resources and focus for developing products, but is risk-averse in using unconventional approaches. ARC will, therefore, serve as a bridge between academia and industry, providing a clear and low-cost pathway to translate creative ideas into products, and thus offering an opportunity to solve an urgent health challenge we face as a human race.